MRC Co-Directors
Matthew Silva, PhD

Matthew Silva, PhD

Orthopaedic Surgery

Focus: Bone biomechanics and mechanobiology. Our lab focuses on two main questions.
1) How does mechanical loading stimulate bone formation?
2) How do bones heal after injury?

Roberto Civitelli

Roberto Civitelli

Internal Medicine – Bone & Mineral Diseases

Focus: the cellular and molecular basis of the bone remodeling process, and to devise mechanisms by which this balance can be modified.

Core A
Matthew Silva, PhD

Matthew Silva, PhD

Orthopaedic Surgery

Focus: Bone biomechanics and mechanobiology. Our lab focuses on two main questions.
1) How does mechanical loading stimulate bone formation?
2) How do bones heal after injury?

Deborah Veis, MD, PhD

Deborah Veis, MD, PhD

Bone & Mineral Diseases

Focus: models of pathological bone loss including osteoporosis, breast cancer metastasis to bone, inflammatory arthritis and osteomyelitis

Roberto Civitelli

Roberto Civitelli

Internal Medicine – Bone & Mineral Diseases

Focus: the cellular and molecular basis of the bone remodeling process, and to devise mechanisms by which this balance can be modified.

Roberta Faccio

Roberta Faccio

Orthopaedic Surgery

Focus: the identification of common molecules that can modulate the activation of immune cells as well as osteoclasts.

Kamilla McGhee

Kamilla McGhee

Administrative Coordinator

Tonia Thompson

Research Administrator

Core B
Simon Tang, PhD

Simon Tang, PhD

Orthopaedic Surgery

Focus: (1) understanding the effect of disease mechanisms on the structure-function relationships of skeletal tissues and (2) developing of translatable therapeutic and regenerative strategies for these diseases. The investigation of these scientific questions includes the application of finite element analyses, multiscale tissue mechanics, the functional imaging of skeletal tissues, and development of nanostructures and nanomaterials for regenerative medicine with in vitro and in vivo biological systems.

Matthew Silva, PhD

Matthew Silva, PhD

Orthopaedic Surgery

Focus: Bone biomechanics and mechanobiology. Our lab focuses on two main questions.
1) How does mechanical loading stimulate bone formation?
2) How do bones heal after injury?

Gretchen  Meyer, PhD

Gretchen Meyer, PhD

Physical Therapy & Neurology

Focus: changes at the molecular and cellular level in skeletal muscle and how they affect muscle structure and function.

Core C
Deborah Veis, MD, PhD

Deborah Veis, MD, PhD

Bone & Mineral Diseases

Focus: models of pathological bone loss including osteoporosis, breast cancer metastasis to bone, inflammatory arthritis and osteomyelitis

Crystal Idleburg, HT(ASCP)

Crystal Idleburg, HT(ASCP)

Senior Research Tech/ Histology

Core D
Farshid Guilak

Farshid Guilak

Orthopaedic Surgery

Focus: cell and tissue engineering; development, degeneration, and aging; embryonic and adult tissue stem cells.

Regis O'Keefe, MD

Regis O’Keefe, MD

Orthopaedic Surgery

Focus: cartilage, bone repair, skeletal development, cancer and inflammatory diseases of bone.

Jie  Shen, PhD

Jie Shen, PhD

Orthopaedic Surgery

Focus: cartilage, bone repair, skeletal development, cancer and inflammatory diseases of bone.