May 15, 2024
St. Louis, Missouri

Washington University Medical School

Eric P. Newman Educational Center

8:30-8:40 amWelcome & Introduction to the Musculoskeletal Research Center
Matthew Silva, PhD, MRC Co-Director
Main Auditorium
Ha-Neui Kim, PhD
University of Arkansas
“NAD+ metabolism in osteoclasts: crosstalk with the
estrogen and mitochondria health”
Main Auditorium
9:25-10:25 amORALS
(7 minute talk + 3 minutes Q&A)
Moderator: Naomi Dirckx, PhD

Elizabeth Hennen
“Hypertension promotes bone loss and bone fragility via immune cell activation”

Nitin Pokhrel, PhD
“HTLV-1 infected T cells cause bone loss via small extracellular vesicles”

Seunghyun Lee
“Stroma-derived Dickkopf-1 suppresses NK cell cytotoxicity in breast cancer”

Gaurav Swarnkar, PhD
“Inflammation compromises bone formation through abnormally accelerated differentiation of osteoblasts to atypical inflammatory osteocyte like cells (aiOCy-L cells)”

Arin Oestreich, PhD
“Maternal conversion of Omega-6 to Omega-3 fatty acids enhances fetal growth and mitigates osteoarthritis related pain behaviors in adult female offspring”

Daniel Palmer
“The chondrocyte “mechanomes”: Activation of the mechanosensitive ion channels TRPV4 and PIEZO1 drives unique transcriptional signatures”
Main Auditorium
10:25-10:45 amMORNING BREAKLobby
10:45-11:30 am



(15 minute talk + 3 minutes Q & A)
Moderator: Aaron Johnson, PhD

Jennifer Zellers, PT, DPT, PhD
“Human Diabetic Tendon Composition: A Data-driven

Rita Brookheart, PhD
“Novel Aspects of Skeletal Muscle Regeneration”
Main Auditorium
11:35-11:55 amSHORT TALKS (part 1)
(3 minute talks)
Moderator: Maria Isabel Menendez Montes, DVM, PhD

Tessa Lochetto
“PPTC7 maintains skeletal muscle homeostasis by suppressing excessive mitophagy”

Brittany Lafaver
“Cardiac function and aging in the osteogenesis imperfecta murine model”

Syeda Lamia, PhD
“Optimal dosing of WNT surrogate stimulates bone formation but not resorption in aged mice”

Hongjun Zheng, PhD
“Enhancing effects of the MicroRNA-181A/B-1 cluster on fracture repair”

Ryan Potter
“Genetic ablation of VEGFA following intervertebral disc injury prevents chronic pain sensitivity”

Nina Tang, PhD
“Transgenic conversion of OMEGA (ω)-6 TO OMEGA (ω)-3 polyunsaturated fatty acids via FAT-1 reduces obesity-related intervertebral disc degeneration”
Main Auditorium
11:55 am-1:15 pmLUNCH + POSTER SESSION 1
(even numbered poster locations, finalist presentations)
Lunch – Lobby
PS1 – Great Rooms A/B
Moderator: Deborah Veis, MD, PhD

Jason Lim, PhD
Assistant Professor
University of Delaware

Corinne Decker, PhD
Associate Director Immuno-Oncology
Main Auditorium
2:05-2:25 pmSHORT TALKS (part 2)
(3 minute talks)
Moderator: Gaurav Swarnkar, PhD

Hua Shen, PhD
“Stem cell extracellular vesicle heterogeneity and its implications for the treatment of tendon injury”

Madison Wissman
“The impact of periacetabular osteotomy on the contralateral hip”

Rebecca Reals
“Anti-Inflammatory Treatment and Active Physical Therapy Have Differing Effects on Functional and Mechanical Properties in a Rat Model of Post-Traumatic Elbow Contracture”

Nidhi Rohatgi, PhD
“Role of BAP1 in regulating epigenetic-metabolic reprogramming of macrophages during inflammatory arthritis”

Dorothy Mims
“NEMO Facilitates Signal Specificity of NF-κB in Basal and Inflammatory Osteoclastogenesis”

Xiao Zhang
“Catecholamine-independent lipolysis provides a master switch for inert adipocyte catabolism and end-stage fat utilization”
Main Auditorium
2:25-3:10 pmPOSTER SESSION 2
(odd numbered poster locations, finalist presentations)
Great Rooms A/B
3:15-4:15 pmKEYNOTE:
Marjolein van der Meulen, PhD
Cornell University
“Musculoskeletal Adaptation to Mechanical Loading”
Main Auditorium
4:15-5:15 pmRECEPTION (with Awards and Science Slam!)Lobby and Great Rooms