Members

Focus: establish robust animal models of chronic low back pain

Focus: using various chemistry, pharmaceutical, and nanomedicine tools to address major problems in the diagnosis and treatment of musculoskeletal, inflammatory and craniofacial/dental diseases

Focus: the role of protein aggregation in hereditary myopathies and motor neuron disease

Focus: the molecular basis of bone metastasis, with a particular interest in the critical roles of osteoclast and osteoblast beta 3 integrin signaling pathway genes, the viral oncogene, Tax, and the bone marrow homing molecules, VLA-4, CXCR4 and G-CSF in the process of bone metastasis and multiple myeloma bone marrow colonization.

Focus: Translating novel technologies from bench to bedside. My work ranges from in vivo to clinical studies and uses computational models to improve the efficacy and efficiency of technology development. Projects address clinical challenges in microsurgery, trauma, and muscle and soft tissue repair.

Focus: the mechanisms contributing to nerve regeneration following surgical reconstruction, specifically the reconstruction of long nerve defects.

Focus: Identifying and evaluating risk factors for rotator cuff disease, with an emphasis on genetic and occupational risk factors. Broad interest is in the interaction between genetic and non-genetic risk factors to influence musculoskeletal disease risk as a means of informing precision prevention approaches.

Focus: Optimize treatment for tendon dysfunction by personalizing dosing of tendon loading and aligning adjunctive treatments to promote the mechanical and biochemical environment needed for tendon repair and remodeling.

Focus: the mechanisms by which osteoclasts degrade bone and as a result our trainees have become the leaders in the field of bone biology.